Leucoderma in early syphilis.

Leucoderma in early syphilis.

CASE 1 A 25-year-old man first noticed depigmented lesions on the face and neck; a few days later he developed asymptomatic erythematous papular and scaly lesions over the trunk and extremities, and moist papular lesions on the scrotal skin. Two weeks later when he reported to us, some of the trunk lesions had also become depigmented. Four months earlier after an extramarital sexual exposure, t...

Secondary syphilis presenting as leucoderma syphiliticum: case report and review

Leucoderma syphiliticum (LS), originally described as syphilide pigmentaire, encompasses a spectrum of dyschromic lesions that emerge during the course of secondary syphilis. Very few case reports are available in modern biomedical databases. We present the case of a 57-year-old HIV-infected male patient who presented with several round to oval, non-scaling, slightly raised and well-demarcated ...

Leucoderma

Leucomelanoderma in early syphilis.

Case Report A 40-year-old priest presented with asymptomatic depigmented and hyperpigmented areas on the palms and the soles of 2i years' duration. The depigmented lesions on the palms had developed first and a month later hyperpigmented lesions appeared nearby. New lesions gradually involved the skin of the backs and sides of the hands and the flexor surface of the wrists. Similar lesions appe...

Erythromycin in early syphilis.

Keller and Morton (1953) first discovered the treponemicidal properties of erythromycin and Turner and Schaeffer (1954) showed that erythromycin came second to penicillin as the most active antibiotic against Treponema pallidum. Kolmer and Rule (1956) attributed treponemicidal properties to erythromycin, but obtained superior results with several other antibiotics. Alexander and Schoch (1954) t...